【文档说明】血管镜观察药物洗脱支架置入后支架表面内膜覆盖课件.pptx，共(22)页，2.076 MB，由小橙橙上传

转载请保留链接：https://www.ichengzhen.cn/view-238815.html

以下为本文档部分文字说明：

AngioscopicFindingsofNeointimalCoverageafterDrugElutingStentImplantationShinsukeNanto,M.D.,PhD.AngioscopicFindi

ngsofNeoint•McFaddenEP,SerryusPWetal.Lancet2004On442daysofDESimplantation,thepatientdevelopedAMIoneweekafteraspirinwasdiscontinu

edbecauseofsurgicaltherapyofcoloncarcinoma.PreprocedureStentimplantationPostprocedureLatestentthrombosisLatethro

mbosisindrug-elutinHondaYandFitzgeraldPJ.Circulation2003;108.FactorsofStentThrombosisCorAngioscopicFindingsofNeointi

malCoverageafterDrugElutingStentImplantationCoronaryangioscply™AngioscopicFindingsofNeoinGrade0Grade1Grade2Grad

e３QuickTime?遣DV/DVCPRO-NTSC闘恚蓈社蒓赦赡菣潜敲蓅蒒蒨缮蔷濠侨菫墙菂钦颣髒黔菑臖Grade0:strutswereexposedsimilarlytothetimeofimp

lantationGrade1:strutswerecovered,butnotembeddedGrade2:strutswereembeddedbytheneo-intima,buttranslucencyseenGrade3:strutswerefu

llyembeddedandinvisiblebyangioscopyKotaniJ,AwataM,NantoS,etal.JACC.2006ClasificationofAngioscopicNeointimalCoverageGrad

es3to6MonthsAfterStentImplantation0255075100Bare-MetalStent(n=22)(%)1007550250IncompletecoverageSirol

imus-ElutingStent(n=15)CompletecoverageGrade3Grade2Grade1Grade0KotaniJ,AwataM,NantoS,etal.JACC.2006NeointimalCoverageGrades3Stent

:Cypher3.5×18mmLocation:RCAmid3.7monthsf-upStent:BxVelocity3.5×23mmLocation:LADmid2.7monthsf-upRepresentativeCases:B

MSvs.ACaseimplantedbothBMSandBare-metalstentFirstfollow-upSecondfollow-upThirdfollow-upNeointimalcoveragegrade0123Sirolimus-elutings

tentn=1n=1n=13n=13n=10n=10n=11n=4n=4n=3n=412months24monthsBare-metalstentFirstfollow-upSecondfollow-upThirdfollow-upNeointimalcove

ragegrade0123Sirolimus-elutingstentn=1n=1n=13n=13n=10n=10n=11n=4n=4n=3n=4４monthsAwataM,KotaniJ,NantoSetal.Circulation.200712months24months４m

onthsChan•ThirtyPESwereangioscopicallycomparedwith36SES.−Intra-andinter-stentheterogeneintyofneointimalcoverageweremorecommoninPES.−Incidenceofthrom

biandyellowplaquesweresimilarbetweenthetwogroups.AwataM,NantoSetal.JACCCardiolIntv2009ComparisonofAngioscopicF

indNeointimalCoverageGradesat8monthsPES(n=30)SES(n=36)Grade0Grade1Grade2Grade3PESvs.SES:p=0.002byχ2testtest(%)AwataM,NantoSetal.JACCCardiolIntv2009N

eointimalCoverageGradesatHomogeneousAwataM,NantoSetal.JACCCardiolIntv2009PESvs.SES:p=0.0006byχ2testHeterogeneityof1g

radePES(n=30)SES(n=36)Heterogeneous53%47%26%48%26%HomogeneityHeterogeneityof2grade74%HomogeneousHeterogeneityofN

eAwataM,NantoS,etal.JACC.2008Cypher3.5×23mmEndeavor3.5×23mmComparisonofAngioscopicFindNeointimalCoverageGradesat8months(%)AwataM,NantoS,etal.JACC

.2008NeointimalCoverageGradesatIncidenceofThrombiandYellowplaquesP=0.2P=0.004ThrombiYellowplaquesIncidenceofThrombiandYelo8mo.afte

rimplantation11mo.afterimplantationAngioscopicFindingsZESPatientFrequencyDistributionsofIn-segmentLateLoss05101520253

0-0.6-0.20.20.61.01.41.82.22.6InsegmentLL(mm)%ofPatientsEndeavorCypher0.13±0.320.34±0.44ResultsofENDEAVOR-IPatientPatientFrequenc

yDistributionsofIn-segmentLateLoss051015202530-0.6-0.20.20.61.01.41.82.22.6InsegmentLL(mm)%ofPatientsEndeavor

Cypher0.13±0.320.34±0.44ResultsofENDEAVOR-IPatient051015202530-0.6-0.20.20.61.01.41.82.22.6InsegmentLL(mm

)%ofPatientsEndeavorCypher0.13±0.320.34±0.44IdealDESTheIdealDESShouldHaveOptSummaryAngiographicfindingsofDESrevealed✓Prolongedde

layedgrowthofneointima✓PoorbuthomogenouscoveringoverSES✓HeterogeneousluminalsurfaceofPES✓Whiteandhomogenousappearanceinpatientstre

atedwithZES:Basicallygrade3neoinitmaAfewyellowplaquesandthrombiSumaryAngiographicfindingso提问与解答环节QuestionsAndAnswers提问与解答环节谢谢聆听

·学习就是为了达到一定目的而努力去干,是为一个目标去战胜各种困难的过程,这个过程会充满压力、痛苦和挫折LearningIsToAchieveACertainGoalAndWorkHard,IsAProcessToOvercomeVariousDifficultiesForAGoal谢聆听

LearningIsToAchieveAC